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Statins May Reduce Death from, Severity of COVID-19 Among Those with Heart Disease or High Blood Pressure

Posted on July 15, 2021

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(HealthNewsDigest.com) – DALLAS, July 15, 2021 — Research published today in The Public Library of Science ONE, PLOS ONE, examined the relationship between use of medications to control cholesterol or blood pressure levels, and the risk of death among people who were hospitalized due to COVID-19.

In an analysis of more than 10,000 hospitalized COVID-19 patients across the United States, the use of cholesterol-lowering drugs, known as statins, prior to admission was associated with a more than 40% reduction in in-hospital death, and a greater than 25% reduction in the risk of developing a severe outcome. The analysis compared similar patients who did and did not use statins or anti-hypertensive medication, among those both with and without underlying health conditions.

“Early during the pandemic, there were questions as to whether certain cardiovascular medications might worsen COVID-19 infections,” said Lori Daniels, M.D., M.A.S., lead author of the study, professor and director of the Cardiovascular Intensive Care Unit at UC San Diego Health. “We found that not only are statins and anti-hypertensive medications safe – they may very well be protective in patients hospitalized for COVID, especially among those with a history of hypertension or cardiovascular disease.”

This research sought to understand the relations between prior medication exposure, existing health conditions and COVID-19 outcomes using data from the American Heart Association’s COVID-19 Cardiovascular Disease Registry. The COVID-19 CVD Registry, powered by the American Heart Association’s Get With The Guidelines® platform, contains de-identified health data on patients treated for COVID-19 at over 140 participating hospitals across the country. As of July 2021, data from more than 49,000 patient records had been contributed into the platform.

“There is much to be learned about the impacts COVID-19 has on the heart and our cardiovascular system,”  said Sandeep R. Das, M.D., MPH, MBA, FACC, FAHA, American Heart Association volunteer expert, COVID-19 CVD Registry committee co-chair and director for quality and value, cardiology division for UT Southwestern Medical Center.  “Research like this is encouraging and has the potential to accelerate treatment patterns as we continue to examine best practices and novel pathways that improve patient outcomes.”

Additional Resources:

  • Available multimedia is on right column of release link:
  • After July 15th, view the manuscript online at PLOS ONE
  • “Prescription” to sit less, move more advised for mildly high blood pressure & cholesterol
  • COVID-19 pandemic magnified health inequities for people with high blood pressure
  • COVID-19 CVD registry details disparities among patients hospitalized with COVID
  • American Heart Association coronavirus (COVID-19) resources for the public
  • American Heart Association COVID-19 Newsroom
  • American Heart Association announces COVID-19 patient data registry
  • Blood pressure chart
  • Follow AHA/ASA news on Twitter @HeartNews
  • Follow news from Stroke, the ASA/AHA journal @StrokeAHA_ASA

The Association receives funding primarily from individuals. Foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and biotech companies, device manufacturers and health insurance providers and the Association’s overall financial information are available here.

About the American Heart Association

The American Heart Association is a relentless force for a world of longer, healthier lives. We are dedicated to ensuring equitable health in all communities. Through collaboration with numerous organizations, and powered by millions of volunteers, we fund innovative research, advocate for the public’s health and share lifesaving resources. The Dallas-based organization has been a leading source of health information for nearly a century. Connect with us on heart.org , Facebook , Twitter or by calling 1-800-AHA-USA1.

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