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Sleep Position and Reflux, New Acute-on-Chronic Liver Failure Guidelines

Posted on February 4, 2022

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(HealthNewsDigest.com) – Bethesda, MD (February 4, 2022) – The February issue of The American Journal of Gastroenterology includes new ACG Clinical Guidelines on acute-on-chronic liver failure, the College’s first set of guidelines on a condition that is emerging as a major cause of mortality among patients with cirrhosis and chronic liver disease. This issue also includes studies of relevance to the general public, including articles on how sleep position affects nocturnal gastroesophageal reflux and the relationship between physical activity and nonalcoholic fatty liver disease, the most common chronic liver condition in the United States. Additional topics include inflammatory bowel disease patient care, endoscopy, hepatitis B, health disparities, colorectal cancer risk, Barrett’s esophagus, and more.

Several articles are highlighted below and access to any articles from this issue, or past issues, is available upon request. The College is also able to connect members of the press with study authors or outside experts who can comment on the articles.

Acute On Chronic Liver Failure Clinical Guidelines
Bajaj, et al.
“In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging as a major cause of mortality. These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of the American College of Gastroenterology.”

Associations Between Sleep Position and Nocturnal Gastroesophageal Reflux: A Study Using Concurrent Monitoring of Sleep Position and Esophageal pH and Impedance
Schuitenmaker, et al.
“The results of this study indicate that the left lateral decubitus position is associated with significantly shorter nocturnal esophageal acid exposure time and faster esophageal acid clearance compared with the supine and right lateral decubitus positions.”

“Physical activity at each intensity is inversely associated with NAFLD prevalence, with larger effects for higher intensities of physical activity. This association is mediated by better metabolic health, mainly lower insulin resistance and waist circumference. Physical activity should therefore be incorporated into NAFLD disease management and prevention programs.”

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