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N.Y.U. Langone Withdraws From Type 1 Diabetes Vaccine Trial in Adolescents

Posted on January 20, 2023

The B.C.G. vaccine, more than a century old, has shown some promise against diabetes. The university’s move left parents and outside investigators concerned.

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Type 1 diabetes is a chronic autoimmune disease in which the body’s immune system attacks and destroys the insulin-producing cells of the pancreas, leading to a lack of insulin. Insulin is a hormone that regulates the amount of sugar (glucose) in the blood. Without insulin, glucose cannot enter the cells of the body, causing high blood sugar levels. Type 1 diabetes typically develops in childhood or adolescence, but it can occur at any age. It’s a lifelong condition that requires daily management with insulin injections or an insulin pump, as well as careful monitoring of blood sugar levels, diet and physical activity. People with type 1 diabetes are at increased risk of complications such as heart disease, kidney disease, nerve damage, and eye problems. With proper treatment and management, people with type 1 diabetes can lead healthy and active lives.

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